The Japanese regulatory agencys biodistribution study (pdf) of the Pfizer vaccine showed that some of the mRNAs moved from the injection site and through the bloodstream, and were found in various organs such as the liver, spleen, adrenal glands, and ovaries of rats 48 hours following injection. As such, finding similar stretches of genes is not novel, unlikely, or particularly surprising. Thank you for taking time to provide your feedback to the editors. "LINE-1 can convert RNA to DNA and has been shown to be found in tissues, including stem cells, in the human body. CLAIM: A Swedish study shows that Pfizer's COVID-19 vaccine changes recipients' DNA. Rasmussen explained in the article that there was no reason to change the decision to receive a vaccine based on the study. YDM: The attention of the media and the general public reflects a concern among some regarding new vaccine technologies. followers 26 videos. A new study from Lund University in Sweden on how the Pfizer-BioNTech COVID-19 vaccine affects human liver cells under experimental conditions, has been viewed more than 800,000 times in just over a week. (In-vitro Swedish Study)\r\rAn accepted and published Swedish study demonstrates for the first time the presence of Pfizer-BionTech vaccine DNA in the cell. The researchers write that the findings warrant a further (in-vitro swedish study) https://lnkd.in/df6hkugy And, this month, we saw a few of the many ways that science can be misinterpreted and misused. In order to create these cell lines, the genetic make-up of the cells has to be fiddled with to make them immortal and keep them alive in the petri dish, Dr. David Strain, a senior clinical lecturer at Englands University of Exeter Medical School, wrote in an email to the AP. Giving to Lund
First, all proteins are made of building blocks known as amino acids. Mandatory vaccinations, the segregation of citizens, and the promotion of inequality in the modern democracy of Greece and other democratic countries in the era of COVID-19. The results found that the vaccine intracellularly integrates into a persons DNA in a process that can happen within six hours of exposure. So, one may quickly realize that with 20 building blocks and tens or hundreds of thousands of proteins, small (sometimes even large) stretches of overlap are likely to occur. For these reasons, while the changes related to LINE-1 are interesting, we cant be sure the effects would be the same in a non-cancerous cell line. In fact. The genetic material delivered by mRNA vaccines never enters the nucleus of your cells, the CDC said on its web page titled Myths and Facts about COVID-19 Vaccines.. doi: 10.1056/NEJMoa2034577. These findings were observed in petri dishes under experimental conditions, but we do not yet know if the converted DNA is integrated into the cells DNA in the genome - and if so, if it has any consequences, Rasmussen says in the article. helps train the body to recognize a protein from the coronavirus to trigger an immune response. Further proof with COVID-19. It is a good tool when studying molecular and cellular processes, they are easy to research, and since the cell lines are easily accessible, studies often start with various cell lines. Shakira. Importantly, LINE-1 has been associated with various disease-related conditions, including cancer. YDM: A previous study from MIT has indicated that the SARS-CoV-2 virus mRNA can be converted to DNA and integrated into the human genome. BNT162b2 mRNA is reverse transcribed intracellularly into DNA as fast as 6 [hours] after BNT162b2 exposure.. The study has received a lot of media attention, what are your thoughts on that? eCollection 2022. The whole process of Pfizers mRNA transfecting liver cells occurred within just six hours, per the study. Huang X, Kong N, Zhang X, Cao Y, Langer R, Tao W. Nat Med. Pfizer Vaccine Becomes DNA in Liver Cells. Both boys were pronounced dead at home. 2022 Dec 7;44(4):72. doi: 10.1007/s40656-022-00548-1. Childrens Hospital of Philadelphia is a charitable 501(c)(3) nonprofit organization. Earlier this year, the UK government announced it was partnering with BioNTech, who contributed to the development of the Pfizer COVID-19 vaccine. Sudden deaths of Canadian Currently the Pfizer-Biontech (mRNA), Sinovac (inactivated virus) and Astrazeneca-Oxford (adenovirus-vector) COVID-19 vaccines are available for vaccination in HK. Ricke DO. DETAILS - Pfizer Vaccine Becomes DNA in The Human Liver Cells Huh7. Materials in this section are updated as new information and vaccines become available. Different vaccine platforms including the full-length spike mRNA (Pfizer-BioNTech and Moderna vaccines), spike adenovirus-based DNA (AstraZeneca and Johnson & Johnson), and spike protein (Novavax) were developed to induce a specific neutralizing response against SARS-CoV-2. Your browser has javascript turned off or blocked. Second, they measured LINE-1 activity. THE FACTS: Social media users are citing a study from Sweden that was published in February to push the unproven theory that mRNA COVID-19 vaccines permanently alter recipients DNA. Shakira. But keep in mind, when the mRNA or adenovirus particles do hit cells outside of the liver or the site of injection, they're still causing them to express Spike protein anchored on their surfaces, not dumping it into the circulation. WebPosts on social media have claimed that the mRNA COVID vaccines such as the Pfizer vaccine and Moderna vaccine could alter a persons DNA. In adifferent study, the spike proteins made in the body after receiving a Pfizer COVID-19 shot have been found on tiny membrane vesicles called exosomesthat mediate cell-to-cell communication by transferring genetic materials to other cellsfor at least four months after the second vaccine dose. Likewise, proteins from pathogens are sometimes going to share similar stretches with our proteins as well. The vaccines mRNA converting into DNA and being found inside the cells nucleus is something that the Centers for Disease Control and Prevention (CDC) said would not happen. We show that the vaccine enters liver cells as This is part of APs effort to address widely shared misinformation, including work with outside companies and organizations to add factual context to misleading content that is circulating online. 8600 Rockville Pike 2021 Jun 7;22(5):172. doi: 10.1208/s12249-021-02058-y. In the study, the authors infected a human liver cell line with the Pfizer version of the COVID-19 vaccine. This is the first time that researchers have shown in vitro or inside a petri dish how an mRNA vaccine is converted into DNA on a human liver cell line, and is what health experts and fact-checkers said for over a year couldnt occur. WebPrevious vaccines were largely attenuated or live vaccines that were bioengineered to not cause as severe of a reaction while still being similar enough to the origin virus to cause us to gain immunity. Indeed, about 8 percent of human DNA comes from viruses inserted into our genomes during evolution. Science X Daily and the Weekly Email Newsletter are free features that allow you to receive your favorite sci-tech news updates in your email inbox, New HIV mRNA vaccine study gets boost from COVID mRNA vaccine development, How gut bacteria can impact treatments for cancer, Human feces and urine contain a motherlode of health data: 'Smart toilets' detect daily fluctuations, serious disease, Multisite multiomic analysis reveals diverse resistance mechanisms in end-stage ovarian cancer, Review of data surrounding COVID vaccines and pregnant women suggest no increased risk of miscarriage, A possible way to prevent or treat lung damage associated with long COVID. This also explains the choice of vaccine concentrations in our study, something we specifically address in the paper, which are 0.52% of the injection site concentration. Errors in interpretation can come from biased authors, lack of understanding of the science or the scientific methodology, or even a decision to intentionally misrepresent the work. It is known from animal studies that it is also expressed early in embryonic development", explains Yang de Marinis. An official website of the United States government. Sudden deaths of Canadian Table S1 summaries the vaccines The vaccine was administered in different amounts and for different lengths of time. WebPfizer Vaccine Becomes DNA in Liver Cells. doi: 10.1128/Spectrum.01162-21. This three-part series was aimed at describing several important aspects of science. doi: 10.1056/NEJMc2107717. 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