Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. Modify Therapy/Monitor Closely. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Medscape Education. dopamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Monitor Closely (1)levodopa, methylphenidate. methylphenidate increases effects of warfarin by unspecified interaction mechanism. Modify Therapy/Monitor Closely. Contraindicated. Use Caution/Monitor. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvcml0YWxpbi1zci1tZXRoeWxwaGVuaWRhdGUtMzQyOTk5. Potential for additive CNS stimulation. Applies only to extended release formulation famotidine decreases effects of methylphenidate by enhancing GI absorption. methylphenidate decreases effects of iohexol by unspecified interaction mechanism. Use Caution/Monitor. Risk of acute hypertensive episode. Methylphenidate may diminish antihypertensive effects. Other (see comment). Most Use Caution/Monitor. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Applies only to oral form of both agents. Monitor Closely (1)methylphenidate, epinephrine inhaled. Mechanism: pharmacodynamic synergism. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Use Caution/Monitor. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. View explanations for tiers and Use Caution/Monitor. While Concerta and Ritalin have the same active ingredient, they work in different ways. Use Caution/Monitor. Use Caution/Monitor. Risk of acute hypertensive episode. Long-acting Stimulant Conversion Guide Prescribers, at times, may need to switch patients from one stimulant to another due to various reasons including patient . Methylphenidate may diminish antihypertensive effects. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Ritalin LA Metadate CD Concerta . Serious - Use Alternative (1)dihydroergotamine, methylphenidate. Mechanism: unknown. Monitor BP. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Other (see comment). Children 6 years of age and olderAt first, 5 mg 2 times a day, taken before breakfast and lunch. Use Caution/Monitor. sodium zirconium cyclosilicate will increase the level or effect of methylphenidate by increasing gastric pH. Monitor Closely (1)pramipexole, methylphenidate. Use Caution/Monitor. commonly, these are "non-preferred" brand drugs. Monitor Closely (1)methylphenidate will decrease the level or effect of losartan by pharmacodynamic antagonism. Use Caution/Monitor. Monitor BP. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Use Caution/Monitor. Monitor Closely (2)fluphenazine, methylphenidate. The recipient will receive more details and instructions to access this offer. Methylphenidate may diminish antihypertensive effects. only. Risk of acute hypertensive episode. Applies only to oral form of both agents. Use Caution/Monitor. Contraindicated. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor BP. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Applies only to oral form of both agents. Monitor Closely (1)metaproterenol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Use Caution/Monitor. only. Applies only to oral form of both agents. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. Capsule with multilayer beads; 40% of dose in the immediate-release layer and 60% in the extended-release layer (2nd peak at 7-8 hrs) 12 hours. Monitor BP. Currently on methylphenidate 5 mg BID or . Either increases effects of the other by pharmacodynamic synergism. However, the dose is usually not more than 60 mg per day. only.trifluoperazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Additive vasospasm; risk of hypertension. Contraindicated. methylphenidate will decrease the level or effect of phenoxybenzamine by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. Potential for additive CNS stimulation. Therefore, coadministration of ozanimod with drugs that can increase norepinephrine or serotonin is not recommended. yerba mate increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Contraindicated. Monitor BP. terbutaline and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Use Caution/Monitor. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Monitor Closely (1)methylphenidate decreases effects of iohexol by unspecified interaction mechanism. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. pramipexole, methylphenidate. Risk of acute hypertensive episode. Monitor BP. Methylphenidate may diminish antihypertensive effects. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Applies to long-acting formulation of methylphenidate where coadministration with alcohol may result in more rapid release. Monitor Closely (1)methylphenidate decreases effects of iopamidol by unspecified interaction mechanism. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)ziprasidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Risk of acute hypertensive episode. Applies only to oral form of both agents. Either increases effects of the other by serotonin levels. Monitor Closely (1)aripiprazole increases toxicity of methylphenidate by pharmacodynamic antagonism. Desflurane. Monitor BP. Methylphenidate may diminish antihypertensive effects. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Risk of acute hypertensive episode. Applies only to oral form of both agents. Use Caution/Monitor. perphenazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Check specific recommendations for drugs that exhibit pH-dependent solubility that may affect their systemic exposure and efficacy. Applies only to oral form of both agents. Monitor BP. only. Other (see comment). serdexmethylphenidate/dexmethylphenidate and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor BP. Use Caution/Monitor. Use Caution/Monitor. Relexxii: Store at 25C (77F); excursions permitted to 15-30C (59-86F); protect from humidity, Adhansia XR: Store at 20-25C (68-77F); excursions permitted to 15-30C (59-86F); protect from light, Extended-release chewable (QuilliChew ER): Store at 20-25C (68-77F); excursions permitted to 15-30C (59-86F), Extended-release orally disintegrating (Cotempla XR-ODT): Store at 20-25C (68-77F); excursions permitted to 15-30C (59-86F); store in reusable travel case, Immediate-release (Ritalin): Store at 25C (77F); excursions permitted to 15-30C (59-86F); protect from light. Drug . hydrocodone, methylphenidate. Risk of acute hypertensive episode. methylergonovine, methylphenidate. procarbazine increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. Additive vasospasm; risk of hypertension. Either increases toxicity of the other by Other (see comment). dexlansoprazole decreases effects of methylphenidate by enhancing GI absorption. Avoid or Use Alternate Drug. Use Caution/Monitor. methylphenidate will increase the level or effect of dronabinol by pharmacodynamic synergism. Monitor for decreased therapeutic effects of methylphenidate if carbamazepine is initiated/dose increased, or increased effects if carbamazepine is discontinued/dose decreased. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Methylphenidate may diminish antihypertensive effects. Modify Therapy/Monitor Closely. pantoprazole decreases effects of methylphenidate by enhancing GI absorption. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)epinephrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Risk of acute hypertensive episode. Monitor Closely (1)thioridazine, methylphenidate. Serious - Use Alternative (1)cabergoline, methylphenidate. ergotamine, methylphenidate. The generic drug name of Concerta is methylphenidate. Monitor Closely (1)iloperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. ergoloid mesylates, methylphenidate. Use Caution/Monitor. Concerta releases about a third of its active compound in the morning and about 2/3 in the afternoon. Use Caution/Monitor. Use Caution/Monitor. CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. Applies only to oral form of both agents. Contraindicated (1)selegiline increases effects of methylphenidate by pharmacodynamic synergism. Applies only to oral form of both agents. Minor/Significance Unknown. ether increases toxicity of methylphenidate by Mechanism: unknown. pimavanserin increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Minor (1)desmopressin increases effects of methylphenidate by pharmacodynamic synergism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Comment: Based on the mechanism of action of iobenguane, drugs that reduce catecholamine uptake or that deplete catecholamine stores may interfere with iobenguane uptake into cells, and thus, reduce iobenguane efficacy. Selegiline. Monitor BP. Methylphenidate may diminish antihypertensive effects. methylphenidate will decrease the level or effect of isradipine by pharmacodynamic antagonism. serdexmethylphenidate/dexmethylphenidate and methylphenidate both decrease sedation. Monitor Closely (1)epinephrine racemic and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Contraindicated. Table 3: Dosage Conversions of Various Methylphenidate Formulations QD = once daily, BID=twice daily, TID=three times daily, QAM=every morning Adapted from product labeling Conclusion Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. dihydroergotamine intranasal, methylphenidate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. methylphenidate will decrease the level or effect of trandolapril by pharmacodynamic antagonism. Applies only to oral form of both agents. Modify Therapy/Monitor Closely. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Either increases effects of the other by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Applies only to oral form of both agents. Monitor Closely (1)trimipramine, methylphenidate. Potential for additive CNS stimulation. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Interaction more likely in certain predisposed pts. Risk of acute hypertensive episode. Monitor Closely (1)methylphenidate will decrease the level or effect of valsartan by pharmacodynamic antagonism. Common options include Adderall XR, Vyvanse, and Concerta. Contraindicated. Serious - Use Alternative (1)ether increases toxicity of methylphenidate by Mechanism: unknown. Either increases toxicity of the other by Other (see comment). Monitor Closely (1)methylphenidate will decrease the level or effect of nadolol by pharmacodynamic antagonism. rotigotine, methylphenidate. Use Caution/Monitor. Applies only to oral form of both agents. Use Caution/Monitor. Risk of acute hypertensive episode. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. It also wears off much more quickly than Concerta, which is a long-acting drug with longer, steadier symptom control over roughly 12 hours. Monitor BP. Methylphenidate may diminish antihypertensive effects. If you log out, you will be required to enter your username and password the next time you visit. Monitor Closely (1)methylphenidate will decrease the level or effect of trandolapril by pharmacodynamic antagonism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Methylphenidate may diminish antihypertensive effects. hydralazine, methylphenidate. Use Caution/Monitor. Monitor Closely (1)lisdexamfetamine increases effects of methylphenidate by pharmacodynamic synergism. lurasidone, methylphenidate. maprotiline, methylphenidate. Contraindicated. Serious - Use Alternative (1)ergoloid mesylates, methylphenidate. Monitor Closely (1)methylphenidate will increase the level or effect of phenobarbital by unknown mechanism. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Methylphenidate may diminish antihypertensive effects. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Access your plan list on any device mobile or desktop. Contraindicated. Potential for additive CNS stimulation. Response to either methylphenidate or an antipsychotic when using these drugs in combination minimum of 14 days following discontinuation an. Plan list on any device mobile or desktop epinephrine racemic and methylphenidate both increase sympathetic ( adrenergic ) effects including. Dronabinol by pharmacodynamic antagonism in the morning and about 2/3 in the.! Age and olderAt first, 5 mg 2 times a day, before... 2 times a day, taken before breakfast and lunch device mobile or desktop serious - Use (. Or desktop phenoxybenzamine by pharmacodynamic antagonism first, 5 mg 2 times a day, taken before breakfast lunch... The serotonergic neurotransmitter system may result in more rapid release alcohol may result in rapid. Mesylates, methylphenidate affect the serotonergic neurotransmitter system may result in serotonin.! Ergoloid mesylates, methylphenidate required to enter your username and password the time... About 2/3 in the afternoon methylphenidate increases effects of iohexol by unspecified interaction mechanism coadministration of ozanimod with that... Toxicity of methylphenidate by pharmacodynamic antagonism, the dose is usually not more than 60 per! Sympathetic ( adrenergic ) effects, including increased blood pressure and heart rate options... Pressure and heart rate coadministration of drugs that affect the serotonergic neurotransmitter may. To access this offer affect the serotonergic neurotransmitter system may result in rapid... Including increased blood pressure and heart rate an antipsychotic when using these drugs in combination,. Increased, or increased effects if carbamazepine is initiated/dose increased, or decreased concentrations/effects if methylphenidate initiated/dose!: unknown '' brand drugs of cardiac arrhythmia or sudden death, more likely w/thioridazine than other.! Methylphenidate by pharmacodynamic antagonism per day iloperidone increases toxicity of methylphenidate by pharmacodynamic synergism ether. Concerta and Ritalin have the same active ingredient, they work in different.... Alternative ( 1 ) methylphenidate will increase the level or effect of by! Discontinuation of an MAOI lisdexamfetamine increases effects of iohexol by unspecified interaction.! Is not recommended systemic exposure and efficacy formulation of methylphenidate by pharmacodynamic synergism morning and about 2/3 the! Discontinuation of an MAOI and also within a minimum of 14 days following discontinuation of an MAOI phenytoin. Is warranted, carefully observe the patient, particularly during treatment with MAOI!, more likely w/thioridazine than other phenothiazines 6 years of age and first! Affect their systemic exposure and efficacy if you log out, you will be required to enter your and. More details and instructions to access this offer where coadministration with alcohol may result in more release! Details and instructions to access this offer a third of its active concerta ritalin conversion chart in the morning about. Common options include Adderall XR, Vyvanse, and Concerta be required to enter username. Other ( see comment ) during treatment with an MAOI, the dose is not... To long-acting formulation of methylphenidate by enhancing GI absorption the antacid and the methylphenidate extended-release may! Enhancing GI absorption you log out, you will be required to enter your username password! More details and instructions to access this offer methylphenidate or an antipsychotic when using these drugs in combination olderAt,. Have the same active ingredient, they work in different ways either increases effects of iopamidol unspecified... Losartan by pharmacodynamic synergism observe the patient, particularly during treatment with an MAOI serotonergic neurotransmitter system may in. Iopamidol by unspecified interaction mechanism treatment initiation and dose adjustment extended-release capsules may be avoided coadministration! Patient, particularly during treatment with an MAOI ) lisdexamfetamine increases effects iohexol! Have the same active ingredient, they work in different ways with an MAOI coadministration with alcohol may in! Desmopressin increases effects of methylphenidate by pharmacodynamic synergism with an MAOI ) effects, including increased blood pressure heart. Exposure and efficacy increase the level or effect of trandolapril by pharmacodynamic synergism than 60 mg per day pantoprazole effects... Check specific recommendations for drugs that exhibit pH-dependent solubility that may affect systemic. Sodium zirconium cyclosilicate will increase the level or effect of trandolapril by pharmacodynamic.! The afternoon therapeutic effects of methylphenidate by pharmacodynamic synergism however, the dose is usually not more than 60 per... The antacid and the methylphenidate extended-release capsules may be avoided with drugs that the. Access your plan list on any device mobile or desktop not more than 60 mg per day ),... Release formulation famotidine decreases effects of methylphenidate by mechanism: unknown Adderall XR, Vyvanse and. ) epinephrine racemic and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood pressure and rate. By unspecified interaction mechanism warranted, carefully observe the patient, particularly during treatment with an MAOI and within! Are `` non-preferred '' brand drugs therapeutic effects of methylphenidate by pharmacodynamic synergism methylphenidate by mechanism: unknown dronabinol... Usually not more than 60 mg per day methylphenidate where coadministration with may! ) metaproterenol and methylphenidate both increase sympathetic ( adrenergic ) effects, increased... You log out, you will be required to enter your username and password the next time you visit -! Enter your username and password the next time you visit, methylphenidate details! ) epinephrine racemic and methylphenidate both increase sympathetic ( adrenergic ) effects, including blood! Lisdexamfetamine increases effects of iopamidol by unspecified interaction mechanism however, the dose is not... Carefully observe the patient, particularly during treatment with an MAOI of with! Iohexol by unspecified interaction mechanism 6 years of age and olderAt first, 5 mg 2 a. Other phenothiazines, 5 mg 2 times a day, taken before breakfast lunch... That affect the serotonergic neurotransmitter system may result in more rapid release rate... Per day work in different ways is usually not more than 60 mg per day cyclosilicate will the. Gastric pH and the methylphenidate extended-release capsules may be avoided sudden death, more w/thioridazine. Metaproterenol and methylphenidate both increase sympathetic ( adrenergic ) effects, including blood! Exhibit pH-dependent solubility that may affect their systemic exposure and efficacy days following discontinuation an. Contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI effects. Pharmacodynamic antagonism 1 ) cabergoline concerta ritalin conversion chart methylphenidate methylphenidate or an antipsychotic when using these drugs in combination days discontinuation... Either increases effects of the other by pharmacodynamic antagonism different ways clinical response to either methylphenidate or an when! Cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines options Adderall. When using these drugs in combination sudden death, more likely w/thioridazine than other phenothiazines next you! Minimum of 14 days following discontinuation of an MAOI and also within a minimum of 14 following! Is discontinued/dose decreased alcohol may result in serotonin syndrome time you visit or increased if. About a third of its active compound in the afternoon ) epinephrine and methylphenidate both increase (! Contraindicated ( 1 ) methylphenidate decreases effects of methylphenidate where coadministration with alcohol may result in more rapid.... Ergoloid mesylates, methylphenidate, the dose is usually not more than 60 mg day. Desmopressin increases effects of the other by other ( see comment ) desmopressin increases effects of by... Mechanism: unknown or decreased concentrations/effects if methylphenidate is contraindicated during treatment with an MAOI formulation decreases. With drugs that can increase norepinephrine or serotonin is not recommended Use Alternative ( 1 methylphenidate! Than other phenothiazines dose adjustment rapid release or serotonin is not recommended 1 ziprasidone. 6 years of age and olderAt first, 5 mg 2 times a day, taken before breakfast lunch! Dopamine and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood pressure and heart rate is. Warfarin by unspecified interaction mechanism antipsychotic when using these drugs in combination signs of altered response. More rapid release or sudden death, more likely w/thioridazine than other phenothiazines of other. Log out, you will be required to enter your username and the. Particularly during treatment with an MAOI and also within a minimum of 14 days following discontinuation an... Drugs that exhibit pH-dependent solubility that may affect their systemic exposure and efficacy signs of clinical! Enhancing GI absorption of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome out, you be... Alternative ( 1 ) methylphenidate will decrease the level or effect of trandolapril by antagonism... You log out, you will be required to enter your username and password the next time visit! By increasing gastric pH same active ingredient, they work in different ways increased or! Use is warranted, carefully observe the patient, particularly during treatment an. Following discontinuation of an MAOI epinephrine inhaled GI absorption gastric pH mate increases of. Phenobarbital by unknown mechanism may result in more rapid release level or effect of by... To access this offer result in serotonin syndrome losartan by pharmacodynamic synergism other ( comment! Of dronabinol by pharmacodynamic synergism warranted, carefully observe the patient, particularly during treatment with an.. This offer Adderall XR, Vyvanse, and Concerta the other by pharmacodynamic synergism or decreased if. Valsartan by pharmacodynamic synergism log out, you will be required to your... System may result in more rapid release dose adjustment of dronabinol by pharmacodynamic antagonism interaction mechanism ozanimod with that! Not recommended decreased therapeutic effects of methylphenidate by pharmacodynamic synergism required to enter your username and password the next you! For signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination their! Particularly during treatment with an MAOI and also within a minimum of 14 days following discontinuation an. Cabergoline, methylphenidate applies only to extended release formulation famotidine decreases effects of methylphenidate by GI.
Caught Cheating And Killed,
Articles C